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- W2364575991 abstract "Objective:To investigate the preventive protection of SSTF on lipid peroxidation damage of ischemia and reperfusion(IR) myocardium in rats.Methods:40 male SD rats were randomly divided into sham operation group,IR group and 3 SSTF groups with 8 rats in each group.The rats in IR group and SSTF groups were established IR rats model;while the rats in 3 SSTF groups were lavaged with SSTF in different dose(17.5,35,70mg/kg/d) 1 week before establishing IR rats model.The SOD activity and MDA content in myocardium were respectively detected.Results:Compared with sham operation group,the SOD activity of myocardium of rats in IR group decreased obviously,MDA content increase obviously(P 0.01).Compared with IR group,the SOD activity of myocardium of rats in 3 SSTF groups increased signif icantly,MDA content decreased signif icantly(P 0.01,P 0.05).The effects of SSTF Ⅱ group and Ⅲ group were better than SSTF Ⅰ group(P0.01,P0.05).There had no remarkable differences between SSTF Ⅱ group and Ⅲ group(P 0.05).Conclusions:SSTF pretreatment can protect ischemia and reperfusion myocardium by lightening lipid peroxidation damage." @default.
- W2364575991 created "2016-06-24" @default.
- W2364575991 creator A5047339449 @default.
- W2364575991 date "2012-01-01" @default.
- W2364575991 modified "2023-09-24" @default.
- W2364575991 title "EFFECTS OF SSTF PRETREATMENT ON LIPID PEROXIDATION DAMAGE OF ISCHEMIA AND REPERFUSION MYOCARDIUM" @default.
- W2364575991 hasPublicationYear "2012" @default.
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