Matches in SemOpenAlex for { <https://semopenalex.org/work/W2364590717> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2364590717 abstract "Objective To study the effects of imipramine and buspirone on spontaneous motor activity, explorative behavior and isolation-induced aggressiveness in mice. Methods Male Kunming mice were isolated for 38～45 days as an animal model of isolation-induced aggression. The isolated mice and group-housed mice were intraperitoneally (IP) administrated with normal saline or different doses of imipramine or buspirone. The aggressiveness of isolated mice was measured 30 minutes after the administration. The exploration and spontaneous motor activity in group-housed mice was measured with the apparatus of locomotion for mice (XZC-4A). Results (1)The latencies (±s) to attacking in imipramine (0, 2.5, 5.0 or 10.0 mg/kg) groups were (52±28), (67± 47),(132±87) and (228±94) seconds respectively, which showed imipramine could dose-dependently increase the latency to attacking and antagonize aggressive behaviors in isolated mice. However, imipramine of same doses did not affect spontaneous motor activity and explorative behavior in group-housed mice. (2)The latencies to attacking in buspirone (2.5, 5.0 and 10.0 mg/kg) group were (215±74), (134±103) and (300±0) seconds respectively, which were significantly different from normal saline group (18±7)seconds and obviously inhibited aggression in isolated mice. Buspirone could also dose-dependently decrease spontaneous motor activity and explorative behavior in group-housed mice. Conclusion Both imipramine and buspirone are of antagonization against aggressive behaviors induced by socially isolation in mice." @default.
- W2364590717 created "2016-06-24" @default.
- W2364590717 creator A5085787730 @default.
- W2364590717 date "2002-01-01" @default.
- W2364590717 modified "2023-09-28" @default.
- W2364590717 title "Anti-aggressive action of imipramine and buspirone in isolated mice" @default.
- W2364590717 hasPublicationYear "2002" @default.
- W2364590717 type Work @default.
- W2364590717 sameAs 2364590717 @default.
- W2364590717 citedByCount "0" @default.
- W2364590717 crossrefType "journal-article" @default.
- W2364590717 hasAuthorship W2364590717A5085787730 @default.
- W2364590717 hasConcept C118552586 @default.
- W2364590717 hasConcept C126322002 @default.
- W2364590717 hasConcept C134018914 @default.
- W2364590717 hasConcept C142724271 @default.
- W2364590717 hasConcept C15744967 @default.
- W2364590717 hasConcept C170493617 @default.
- W2364590717 hasConcept C204787440 @default.
- W2364590717 hasConcept C2775864247 @default.
- W2364590717 hasConcept C2776175493 @default.
- W2364590717 hasConcept C2777287423 @default.
- W2364590717 hasConcept C2777397205 @default.
- W2364590717 hasConcept C2779145073 @default.
- W2364590717 hasConcept C2779448149 @default.
- W2364590717 hasConcept C2985495968 @default.
- W2364590717 hasConcept C71924100 @default.
- W2364590717 hasConcept C98274493 @default.
- W2364590717 hasConceptScore W2364590717C118552586 @default.
- W2364590717 hasConceptScore W2364590717C126322002 @default.
- W2364590717 hasConceptScore W2364590717C134018914 @default.
- W2364590717 hasConceptScore W2364590717C142724271 @default.
- W2364590717 hasConceptScore W2364590717C15744967 @default.
- W2364590717 hasConceptScore W2364590717C170493617 @default.
- W2364590717 hasConceptScore W2364590717C204787440 @default.
- W2364590717 hasConceptScore W2364590717C2775864247 @default.
- W2364590717 hasConceptScore W2364590717C2776175493 @default.
- W2364590717 hasConceptScore W2364590717C2777287423 @default.
- W2364590717 hasConceptScore W2364590717C2777397205 @default.
- W2364590717 hasConceptScore W2364590717C2779145073 @default.
- W2364590717 hasConceptScore W2364590717C2779448149 @default.
- W2364590717 hasConceptScore W2364590717C2985495968 @default.
- W2364590717 hasConceptScore W2364590717C71924100 @default.
- W2364590717 hasConceptScore W2364590717C98274493 @default.
- W2364590717 hasLocation W23645907171 @default.
- W2364590717 hasOpenAccess W2364590717 @default.
- W2364590717 hasPrimaryLocation W23645907171 @default.
- W2364590717 hasRelatedWork W1981170622 @default.
- W2364590717 hasRelatedWork W1997455773 @default.
- W2364590717 hasRelatedWork W2011718923 @default.
- W2364590717 hasRelatedWork W203965366 @default.
- W2364590717 hasRelatedWork W2049518455 @default.
- W2364590717 hasRelatedWork W2052096582 @default.
- W2364590717 hasRelatedWork W2053917460 @default.
- W2364590717 hasRelatedWork W2076795082 @default.
- W2364590717 hasRelatedWork W2082894743 @default.
- W2364590717 hasRelatedWork W2084339590 @default.
- W2364590717 hasRelatedWork W2126374504 @default.
- W2364590717 hasRelatedWork W2195319487 @default.
- W2364590717 hasRelatedWork W2355709502 @default.
- W2364590717 hasRelatedWork W2381873837 @default.
- W2364590717 hasRelatedWork W2462046461 @default.
- W2364590717 hasRelatedWork W2473510258 @default.
- W2364590717 hasRelatedWork W2499495449 @default.
- W2364590717 hasRelatedWork W2773119910 @default.
- W2364590717 hasRelatedWork W3187371517 @default.
- W2364590717 hasRelatedWork W1497868593 @default.
- W2364590717 isParatext "false" @default.
- W2364590717 isRetracted "false" @default.
- W2364590717 magId "2364590717" @default.
- W2364590717 workType "article" @default.