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- W2364609932 abstract "Objective To investigate the effection on the lymphocyte induced by sertoli cell form rat,and provide clues for setting up the immunoprivilege.Methods Processing the young rat's testicle using enzyme degisting method and get the sertoli cell,stimulating the T,B lymphocytes respectively using mitogen ConA and LPS.The vitality of the lymphocyte that had been cultured with sertoli cell culture supernatants was measured using MTT method.Measuring(by Annexin V/PI method) the apoptosis rate of cells that have been affected by the sertoli cell culture supernatants.Results Sertoli cell supernatants can obviously inhibit the proliferation effect on the lymphocyte induced by mitogens,and increase the apoptosis rate of these two kinds of lymphocyte(34.5Vs29.9 and 48.6Vs33.9).Conclusion Sertoli cell supernatants can lead to increase the apoptosis rate of activated T,B cells and to suppress their proliferation activated by mitogens." @default.
- W2364609932 created "2016-06-24" @default.
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- W2364609932 date "2010-01-01" @default.
- W2364609932 modified "2023-09-23" @default.
- W2364609932 title "Primary study for the effection on lymphocyte induced by rat sertoli cell" @default.
- W2364609932 hasPublicationYear "2010" @default.
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