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- W2364614902 abstract "Objective:To investigate the association between VEGF-460 TC(rs833061) polymorphism and susceptibility to psoriasis.Methods:The informations of the studies on the association between VEGF-460 TC(rs833061) polymorphism and susceptibility to psoriasis were retrieved and collected from Pubmed,Embase,Cochrane Library,CNKI,VIP,Wanfang and CBD.Meta-analysis was used to test heterogeneity and publication bias,and the odds ratio(OR) and 95%confidence interval(CI) were also calculated.RevMan 5.2 and Stata 12.0 software were applied for statistical processing.Results:Five review articles were involved in this study,including 698 cases and 866 controls.The results of overall meta-analysis showed no significant association between VEGF-460 TC(rs833061) polymorphism and susceptibility to psoriasis.The subgroup analysis based on ethnicity revealed that the VEGF-460 TC(rs833061) polymorphism was significantly associated with a decreased risk of psoriasis in Europeans,but no significant association was observed in Asians.Conclusions:The VEGF-460TC(rs833061) polymorphism is more likely to be associated with the susceptibility to psoriasis in Europeans,but not in Asians.The individuals with CC+CT and CT genotype may have a decreased risk of psoriasis in European." @default.
- W2364614902 created "2016-06-24" @default.
- W2364614902 creator A5078930014 @default.
- W2364614902 date "2014-01-01" @default.
- W2364614902 modified "2023-09-24" @default.
- W2364614902 title "A meta-analysis on asociation of VEGF-460 T>C polymorphism with susceptibility to psoriasis" @default.
- W2364614902 hasPublicationYear "2014" @default.
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