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- W2364625557 abstract "Objective To investigate the effects of resveratrol(Res) on platelet function in rats with severe acute pancreatitis(SAP).Methods SAP was induced in rats.Rats were divided into 3 groups(12 rats in each group): Sham group,SAP group and Res group.Indices of platelet function including platelet aggregation rate in first minute(PAR-1),maximal platelet aggregation rate(PAR-m),platelet adhesion rate(PAR) and the levels of GMP-140,TXB2 in plasma were determined after model establishment 6 h,12 h in above-mentioned three groups.Results The PAR-1,PAR-m,PAR and the levels of GMP-140,TXB2 in plasma were significantly increased in rats after induction of SAP(P0.05).In Res group the PAR-1 and the levels of GMP-140,TXB2 in plasma were obviously lower than that in SAP group and Sham group(P0.05).Conclusion The ability of platelet adhesion and aggregation,the levels of GMP-140 and TXB2 in plasma significantly increase after SAP.Res can partially reduce the degree of platelet activation and improve the platelet function of aggregation,adhension and release." @default.
- W2364625557 created "2016-06-24" @default.
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- W2364625557 date "2011-01-01" @default.
- W2364625557 modified "2023-09-23" @default.
- W2364625557 title "Effects of resveratrol on platelet function in rats with severe acute pancreatitis" @default.
- W2364625557 hasPublicationYear "2011" @default.
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