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- W2364653537 abstract "Objective To compare the postoperation outcome among different temperature for hypothermic circulation arrest with antegrade cerebral perfusion in aortic arch surgery,to determine which temperature provides best brain protection.Methods Pubmed,Embase and Cochrane Library were searched for studies reporting on the postoperation outcome in aortic arch replacement with different hypothermic circulation arrest with antegrade cerebral perfusion.Two principle investigators respectively extracted the information for Meta-analysis.Meta-analyses were conducted using STATA version 11.2.Analysis of heterogeneity was performed with the Cochrane Q statistic and the I2statistics.Results 8 studies were selected to analysis,no less than 3 studies could be used to analysis the result between every two different groups.Pooled analysis showed that Mild hypothermic circulation arrest(Mild HCA) group patients had lower percentage of,emergency,aortic dissection and aortic arch replacement than the other two groups.However,there were no significant differences for mortality among Mild,Moderate and Deep hypothermic circulation arrest groups[OR1=0.74,95%CI(0.35,1.55),ORl =0.31,95%CI(0.06,1.50),OR3 =0.83,95%CI(0.43,l.50)],similar rates of temporary neurologic dysfunction(TND)[OR 1 =0.82,95%CI(0.43,1.56),OR2 =0.68,95%CI(0.25,1.80),OR3 =0.68,95%CI(0.38,1.23)],also similar rates of permanent neurologic dysfunction(PND)[OR1=0.75,95%CI(0.16,3.45),OR2 =0.20,95%CI(0.04,1.14),OR3 = 0.78,95%CI(0.29,2.14)].Conclusions Deep hypothermic circulation arrest(DHCA) and Moderate hypothermic circulation arrest(Moderate HCA) with antegrade cerebral perfusion offer effective cerebral and neurological protection,Mild hypothermic circulation arrest(Mild HCA) may not suitable to use in complex aortic arch surgery." @default.
- W2364653537 created "2016-06-24" @default.
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- W2364653537 date "2013-01-01" @default.
- W2364653537 modified "2023-09-26" @default.
- W2364653537 title "Effects of mild,moderate or deep hypothermic circulation arrest with antegrade cerebral perfusion in aortic arch surgery:a Meta-analysis" @default.
- W2364653537 hasPublicationYear "2013" @default.
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