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- W2364654140 abstract "Objective To estimate the feasibility of applying cancellous bone matrix(CBM) as the cell scaffold for periodontal tissue engineering.Methods Dog autogenous periodontal ligament cells(PDLCs) cultured in vitro were collected and seeded on the three-dimensional scaffolds of CBM.The growth of cells on the scaffolds was observed with scanning electronic microscope.Then the PDLCs/CBM composites were transplanted into man-made periodontal defects,and the groups filled with nothing or filled with only CBM were the controls.The dogs were sacrificed 8 weeks later and the periodontium regeneration was observed histologically.Results Scanning electronic microscope showed the flourishing growth of cells on the CBM scaffolds which were in porous structure.The histological observation showed that the PDLCs/CBM group exhibited more new bone,new periodontal ligament and new cementum occupying the majority of the defects than the control groups,and epitheliums were not observed.Conclusions The study proves that CBM can be used as the cell scaffolds for periodontal tissue engineering." @default.
- W2364654140 created "2016-06-24" @default.
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- W2364654140 date "2012-01-01" @default.
- W2364654140 modified "2023-09-26" @default.
- W2364654140 title "A study on periodontal tissue engineering with cancellous bone matrix as the cell scaffold" @default.
- W2364654140 hasPublicationYear "2012" @default.
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