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- W2364662999 abstract "Objective:To investigate the effect of pH,temperature and light on stability of desmopressin acetate.Methods:An adjusted HPLC method was employed to determine concentration loss of desmopressin acetate under these experimental factors mentioned above.The degradation calculations of desmopressin acetate under different pH conditions were obtained by regulation analysis between proportion of the remaining and time,whose slopes indicated the sensitivity of the drug stability to these influencing factors.Results:Acid environment,basic condition,high temperature and sunlight could accelerate desmopressin acetate's decomposition,and it would be more stable when pH value was between 4 and 5.Conclusions:Desmopressin acetate is unstable under basic condition,high temperature and sunlight." @default.
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- W2364662999 date "2013-01-01" @default.
- W2364662999 modified "2023-09-27" @default.
- W2364662999 title "Effect of pH,temperature and light on stability of desmopressin acetate" @default.
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