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- W2364665203 abstract "Objective To explore the cytotoxicity of F-141b in V79 Chinese hamster cells in vitro.Methods V79 cells suspension were exposed in different concentration(0、10、20、30、40、50 and 60 ml/l) F-141b agent and incubated at 37 °C for different time(3、6、12、24 and 48 h).The number of living cells was counted under microscope.The survival rate and IC50 was observed.Results In any period of definite time,the survival rate of V79 cell decreased gradually with increasing concentration of F-141b.On the other hand,at the same concentration of F-141b,the longer the incubation was,the less the survival rate of V79 cell was.There was clear discrepancy between short incubations(3 h、6 h) and long incubations(24 h、48h)(P0.05).And there was also clear discrepancy among different concentration groups(P0.05).Otherwise there was statistical significance among co-linearity in 3 h、12 h、48 h groups.IC50 in the 24 h group was 32.37ml/L.Conclusion With this experiment condition,F-141b could in-duce cytotoxicity and is in a dose-dependent and time-dependent manner." @default.
- W2364665203 created "2016-06-24" @default.
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- W2364665203 date "2009-01-01" @default.
- W2364665203 modified "2023-09-23" @default.
- W2364665203 title "The Cytotoxicity of F-141b in V79 Chinese Hamster Cells in vitro" @default.
- W2364665203 hasPublicationYear "2009" @default.
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