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- W2364666411 abstract "High mobility group box1(HMGB1) is a traditional DNA binding protein and a strong inflammatory cytokine which exists in a variety of eukaryotic cell nucleus.HMGB1 can be secreted actively by natural immune cells such as the monocyte/macrophage stimulated by the inflammatory cells factor,and also can be released passively by necrotic cells.Besides participating in the construction of nucleosome,stablizing,and regulating gene transcription,the molecule can also spur inflammation cell activation and gathering to inflammatory parts,promoting inflammation cell factor secretion and causing tissue damage.HMGB1 is also involved in the process of pregnancy,and its abnormal expression will lead to pregnancy-induced hypertension,miscarriage,premature rupture of fetal membranes,and other pregnancy-related diseases." @default.
- W2364666411 created "2016-06-24" @default.
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- W2364666411 date "2013-01-01" @default.
- W2364666411 modified "2023-09-28" @default.
- W2364666411 title "Research Progress of High Mobility Group Box1 and Related Pathological Pregnancy" @default.
- W2364666411 hasPublicationYear "2013" @default.
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