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- W2364671493 abstract "Objective:To investigate histologically and histometrically the changes of pulpal lesions in control and cyclosporin A(CyA) treated rats.Methods:The pulps of the first lower molars of nine normal and nine CyA treated rats were exposed and left open into the oral cavity.Three animals of each group were sacrificed after 3,7 and 14 days of the pulp exposure.The specimens were sectioned sagittally at a thickness of 5μm and evaluated histologically and histometrically.Results:Histologically,the pulpal necrosis extended gradually from the coronal part of the pulpal tissue to the apex after pulp exposure.The pulpal inflammation of CyA teated group was weaker than that of control group.Histometrically,the length of pulpal necrosis increased gradually from 3 to 14 days.The pulpal lesions were smaller in CyA treated group than those of controlled group in all studied periods,and the differences between both groups were statistically significant.Conclusion:CyA can inhibit the development of pulpal lesions in rats. [" @default.
- W2364671493 created "2016-06-24" @default.
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- W2364671493 date "2001-01-01" @default.
- W2364671493 modified "2023-09-27" @default.
- W2364671493 title "Effect of Cyclosporin A on the Progression of Pulpal Lesions" @default.
- W2364671493 hasPublicationYear "2001" @default.
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