FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2364671638> ?p ?o ?g. }

• W2364671638 abstract "Objective To investigate clinical significance of myeloid-derived suppressor cells(MDSCs) in peripheral blood in the progression of HBV-related acute-on-chronic liver failure(HBV-ACLF). Methods Totally 45 HBV-ACLF patients, 34 pa- tients with chronic hepatitis B(CHB) and 25 healthy controls(HC) were enrolled in the study. Flow cytometry was applied to detect the frequencies of MDSCs in peripheral blood. HBV-ACLF patients were given a three-week follow-up, and were divided into an improved group and an ineffective group according to the clinical efficacy. The changes of the frequencies of MDSCs in peripheral blood in the improved group and the ineffective group were observed dynamically. Results The frequencies of MDSCs in peripheral blood in HBV-ACLF group(1.53% ±1.15%) were significantly higher than those in CHB group(0.92% ±0.46%) and those in HC group(0.91%±0.47%)(P0.01). The frequency of MDSCs in peripheral blood in HBV-ACLF group was positively correlated with TBIL(r=0.434, P=0.003), CRE(r=0.343, P=0.021), international normalized ratio(INR)(r=0.505, P=0.000), model for end-stage liver disease(MELD) score(r=0.528, P=0.000) and MELD-Na score(r=0.451, P=0.002), and had a multiple linear relationship with INR and TBIL(the regression model: =-0.781+0.623×INR+0.003×TBIL). The HBV-ACLF patients who died within 3 weeks had higher frequencies of MDSCs in peripheral blood(2.09%±1.51%) than the improved group(1.15%±0.56%) and the ineffective group(1.17%±0.70%)(P0.05). The frequencies of MDSCs in peripheral blood had a weak rank correlation with the prognosis of the pa- tients(r=0.309, P=0.039). The follow-up showed the frequencies of MDSCs in peripheral blood were not significantly different in the improved group and the ineffective group. Conclusions The frequency of MDSCs in peripheral blood in HBV-ACLF patients in- creases significantly. It is correlated with the prognosis of HBV-ACLF patients. The higher the frequency of MDSCs in peripheral blood is, the poorer prognosis the HBV-ACLF patients have." @default.
• W2364671638 created "2016-06-24" @default.
• W2364671638 creator A5019855876 @default.
• W2364671638 date "2013-01-01" @default.
• W2364671638 modified "2023-09-28" @default.
• W2364671638 title "Expression of myeloid-derived suppressor cells in peripheral blood in patients with HBV-related acute-on-chronic liver failure" @default.
• W2364671638 hasPublicationYear "2013" @default.
• W2364671638 type Work @default.
• W2364671638 sameAs 2364671638 @default.
• W2364671638 citedByCount "0" @default.
• W2364671638 crossrefType "journal-article" @default.
• W2364671638 hasAuthorship W2364671638A5019855876 @default.
• W2364671638 hasConcept C121608353 @default.
• W2364671638 hasConcept C126322002 @default.
• W2364671638 hasConcept C179185449 @default.
• W2364671638 hasConcept C203014093 @default.
• W2364671638 hasConcept C2522874641 @default.
• W2364671638 hasConcept C2777382497 @default.
• W2364671638 hasConcept C2778019345 @default.
• W2364671638 hasConcept C2780593183 @default.
• W2364671638 hasConcept C3017910909 @default.
• W2364671638 hasConcept C46762472 @default.
• W2364671638 hasConcept C553184892 @default.
• W2364671638 hasConcept C55721878 @default.
• W2364671638 hasConcept C71924100 @default.
• W2364671638 hasConcept C90924648 @default.
• W2364671638 hasConceptScore W2364671638C121608353 @default.
• W2364671638 hasConceptScore W2364671638C126322002 @default.
• W2364671638 hasConceptScore W2364671638C179185449 @default.
• W2364671638 hasConceptScore W2364671638C203014093 @default.
• W2364671638 hasConceptScore W2364671638C2522874641 @default.
• W2364671638 hasConceptScore W2364671638C2777382497 @default.
• W2364671638 hasConceptScore W2364671638C2778019345 @default.
• W2364671638 hasConceptScore W2364671638C2780593183 @default.
• W2364671638 hasConceptScore W2364671638C3017910909 @default.
• W2364671638 hasConceptScore W2364671638C46762472 @default.
• W2364671638 hasConceptScore W2364671638C553184892 @default.
• W2364671638 hasConceptScore W2364671638C55721878 @default.
• W2364671638 hasConceptScore W2364671638C71924100 @default.
• W2364671638 hasConceptScore W2364671638C90924648 @default.
• W2364671638 hasLocation W23646716381 @default.
• W2364671638 hasOpenAccess W2364671638 @default.
• W2364671638 hasPrimaryLocation W23646716381 @default.
• W2364671638 hasRelatedWork W1564659884 @default.
• W2364671638 hasRelatedWork W1971977916 @default.
• W2364671638 hasRelatedWork W2092545922 @default.
• W2364671638 hasRelatedWork W2105974208 @default.
• W2364671638 hasRelatedWork W2164836744 @default.
• W2364671638 hasRelatedWork W2350033748 @default.
• W2364671638 hasRelatedWork W2351825313 @default.
• W2364671638 hasRelatedWork W2357378434 @default.
• W2364671638 hasRelatedWork W2357446187 @default.
• W2364671638 hasRelatedWork W2360471005 @default.
• W2364671638 hasRelatedWork W2361737583 @default.
• W2364671638 hasRelatedWork W2364196205 @default.
• W2364671638 hasRelatedWork W2366878586 @default.
• W2364671638 hasRelatedWork W2387870188 @default.
• W2364671638 hasRelatedWork W2387876827 @default.
• W2364671638 hasRelatedWork W2389831310 @default.
• W2364671638 hasRelatedWork W2390136135 @default.
• W2364671638 hasRelatedWork W2594996607 @default.
• W2364671638 hasRelatedWork W2996172866 @default.
• W2364671638 hasRelatedWork W3205681550 @default.
• W2364671638 isParatext "false" @default.
• W2364671638 isRetracted "false" @default.
• W2364671638 magId "2364671638" @default.
• W2364671638 workType "article" @default.