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- W2364677493 abstract "Objective:To estimate the effect of 4% succinylated gelatin in lower epidural anesthesia for elderly patients scheduled for open reduction and internal fixation from lower limb fractures. Methods:Ninety patients aged from 65 to 95, ASA II to III grade, were prospectively randomized into three groups with 30 in each. Group A received Ringer′s solution 500 ml (20 ml/min) 10 min before test with a dose of 2% lidocaine 5 ml, group B were given succinylated gelatin 500 ml instead of Ringer′ solution when the blood pressure dropped and group C received succinylated gelatin 500 ml( 20 ml/min) 10 min before the test with a dose of 2% lidocaine 5 ml. SBP, DBP and HR at the point of before administration (T-0), 5 min after administration (T-1), 15 min after administration (T-2) were recorded, and the dosage of ephedrine used as well. Results: SBP and DBP were significantly decreased from T-0 to T-2 in group A and B, but with no significant change in group C. There showed significant difference in ephedrine usage when group A(80%) and B ( 50%) compared with group C (13.3%). Conclusion:Prophylactic administration of succinylated gelatin in elderly patients under low level continuous epidural anesthesia can effectively maintain circulatory stability in the early stage of anesthesia and reduce the percentage of usage of vasoactive agent ." @default.
- W2364677493 created "2016-06-24" @default.
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- W2364677493 date "2008-01-01" @default.
- W2364677493 modified "2023-09-26" @default.
- W2364677493 title "Clinical application of 4% succinylated gelatin in lower epidural anesthesia for elderly patients" @default.
- W2364677493 hasPublicationYear "2008" @default.
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