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- W2364681730 abstract "[Objective] Through the experiment of using bioartificial nerve substitute for nerve autograft to repair the nerve defect, we expect to provide for further study of tissue engineering ioartificial nerve and its clinical practice. [Methods] Rat′s sciatic nerve defect being repaired according to the following three ways: conduits with Schwann cells(group A); conduits without Schwann cells (group B) and autologous nerves (group C). Evaluation of its feasibility for promoting nerve regeneration included general observation, muscle measurement, electrophysiological examination, histomorphologically analysis was done after 10 weeks of operation. [Results] Schwann cells and the PLGA filament could form cell-biomaterials complex body. At the end of 10 weeks after operation, the relative weight of the triceps surae muscle, myelinated fibers, the AMP, AREA, NCV of regenerated nerve of group A and C were significantly better than group B, and there was no significant difference compared to group C. [Conclusion] It was showed that PLGA was compatible with Schwann cells and suitable to construct tissue-engineered bioartificial nerve.and its effect of repairing the nerve defect was similar to autologous nerves." @default.
- W2364681730 created "2016-06-24" @default.
- W2364681730 creator A5034956291 @default.
- W2364681730 date "2006-01-01" @default.
- W2364681730 modified "2023-09-24" @default.
- W2364681730 title "Experiment of tissue engineering bioartificial nerve graft in repair of peripheral nerve" @default.
- W2364681730 hasPublicationYear "2006" @default.
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