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- W2364689024 abstract "Objective Nogo-A is found widespread in both myelin and neurons of central nervous system in several ways of subcellular localization. Based on our previous research work, to get further evidence for intranuclear localization of Nogo-A by checking the subcellular localization of nogo-A / B in rat brain tissue. Methods Relatively pure nuclear fraction was got from rat cortex and cerebellum by differential centrifugation and NP-40. Then the expression of Nogo-A in the subcellular fractions were checked by Western blot. By double immunofluorescen, subcellular localization of Nogo-A was observed under confocal microscope. Result Clear Nogo-A band could be detected in purified nuclear fractions by Western blot. According to the immunofluorescen, positive signals were mainly found in the nucleus. Conclusion Nogo-A exists in nucleus of rat cortex and cerebellum and probably goes into the nucleus in the form of full length." @default.
- W2364689024 created "2016-06-24" @default.
- W2364689024 creator A5060511465 @default.
- W2364689024 date "2009-01-01" @default.
- W2364689024 modified "2023-09-23" @default.
- W2364689024 title "Intranuclear localization of Nogo-A in rat brain" @default.
- W2364689024 hasPublicationYear "2009" @default.
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