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- W2364697852 abstract "Objective: To investigate the association of 2 single nucleotide polymorphisms (SNP) at positions -550 and -221 in the promoter of the mannose-binding lectin(MBL)gene with susceptibility to juvenile idiopathic arthritis (JIA). Methods: Sequence specific priming-polymerase chain reaction(SSP-PCR)were used to investigate the SNPs of the promoter region of the MBL gene in 50 patients with JIA and 48 healthy children. Results: Three haplotype, HY, LY, and LX, were present in both groups, and no HX haplotype was found. And no statistically significant differences were observed when the haplotype distributions between JIA patients and healthy controls were compared. Conclusion: Our results provide no evidence for genetic association conferred by the SNPs in the promoter of the MBL gene with respect to susceptibility of JIA." @default.
- W2364697852 created "2016-06-24" @default.
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- W2364697852 date "2006-01-01" @default.
- W2364697852 modified "2023-09-26" @default.
- W2364697852 title "Study of single nucleotide polymorphisms in the promoter of mannose-binding lectin gene in patients with juvenile idiopathic arthritis" @default.
- W2364697852 hasPublicationYear "2006" @default.
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