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- W2364698199 abstract "Objective:To learn whether the various activation of ventricular myocardiocyte KATP results in electrophysiological heterogeneity by dealing with pinacidil.Methods:The New Zealand rabbits were treated with heparin.Then the single ventriculo-myocardiocyte was isolated from the rabbit heart with Taniguchi method.The whole cell record with patch clamp was performed for all single cells in 12 hours.Results:The action potential duration (APD) is shorten with the pinacidil level(r=-0.967,P0.01),but the action potential amplitude (APA) (r=0.038,P0.01),the maximal velocity in 0 phase of action potential(Vmax) ( r=0.106,P0.01) is rarely affected.Conclusions:Different level of pinacidil results in different APD change,shorter with higher level of pinacidil.These results indicate that the various activation of KATP may electrophysiological heterogeneity." @default.
- W2364698199 created "2016-06-24" @default.
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- W2364698199 date "2010-01-01" @default.
- W2364698199 modified "2023-09-25" @default.
- W2364698199 title "The Effect of the Various Activation of Pinacidil in Electrophysiological Heterogeneity" @default.
- W2364698199 hasPublicationYear "2010" @default.
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