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- W2364700435 abstract "Objective To screen polymorphisms in exon183141TG of PTCH gene and to detect whether this polymorphic site was associated with sporadic keratocystic odontogenic tumor(KCOT).Methods Sixty-four patients with KCOT and seventy-five healthy controls were recruited for the study with informed consent.Genomic DNAs were recruited for the study with informed consent.Genomic DNAs were obtained from peripheral blood of KCOT patients and healthy controls.The PCR-based restriction fragment length polymorphism analysis was performed for PTCH exon183141TG genotyping.Results The frequency of genotype and allele of the SNPs was complied with the Hardy-Weinberg equilibrium.The TT genotype and T alleles frequencies were significantly lower in KCOT patients than in those of healthy controls(P0.05).Conclusion Our findings demonstrate that the SNP of exon183141 may be associated with the susceptibility of sporadic KCOT development in Chinese." @default.
- W2364700435 created "2016-06-24" @default.
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- W2364700435 date "2009-01-01" @default.
- W2364700435 modified "2023-09-23" @default.
- W2364700435 title "The relationship between polymorphism of PTCH gene and sporadic keratocystic odontogenic tumor" @default.
- W2364700435 hasPublicationYear "2009" @default.
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