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- W2364703733 abstract "Peroxisome proliferator activated receptor(PPAR) is a member of receptor superfamily and is classified inito three subtypes:PPAR α,β and γ.The main function of PPAR is to regulate the transcription of genes.Lipid lowering fibrates specifically bind to PPARα,while antidiabetic TZDs are ligands for PPARγ.Fibrates decrease hyperinsulinemia and hypertriglyceridemia,and improve the action of insulin on stimulating glucose metabolism by activation of PPARα.TZDs significantly attenuate hyperinsulinemia in animals with insulin resistance and hyperglycemia in diabetic patients through activation of PPAR γ." @default.
- W2364703733 created "2016-06-24" @default.
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- W2364703733 date "2000-01-01" @default.
- W2364703733 modified "2023-09-24" @default.
- W2364703733 title "Peroxisome proliferator activated receptors and insulin resistance" @default.
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