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- W2364705154 abstract "] Objective Magnetic resonance diffusion tensor imaging(MR-DTI) can reflect the diffusion features of water molecules in vivo,which can not only provide functional details of the living body,but also undertake accurate parametric analysis.Predicting radiation damage of the temporal lobes in nasopharengeal carcinoma(NPC) patients by MR-DTI to help early diagnosis and lessen complications is of prime importance.But the regionality of NPC limited its researches with large samples and longitudinal comparing.This study analyzed the temporal lobe white matter′s water diffusion characteristics in the NPC patients before and after radiotherapy to provide references for detecting radiation damage progression.Methods There were 204 cases of NPC patients underwent brain routine MRI and MR-DTI scans.In which 44 cases were pre-radiation patients,160 cases were post-radiation patients and 22 cases had MR scans both pre-and post-radiation in 3-5 months.Isotropic apparent diffusion coefficient(ADCiso) and fractional anisotropic(FA) values were measured in bilateral temporal lobes in all cases and were analyzed with longitudinal comparison.Results ADCiso and FA values decreased after radiation,while remarkable changes were found in 3-5 months.After 6 months,ADCiso and FA values tended to elevate.Conclusion The temporal lobe white matter′s water diffusion characteristics can be evaluated using the MR-DTI technique,which can help monitor the degree of radiation damage and comprehend its repair process." @default.
- W2364705154 created "2016-06-24" @default.
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- W2364705154 date "2011-01-01" @default.
- W2364705154 modified "2023-09-23" @default.
- W2364705154 title "Detecting radiation damage of temporal lobes in nasopharengeal carcinoma patients based on MR diffusion tensor imaging" @default.
- W2364705154 hasPublicationYear "2011" @default.
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