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- W2364706098 abstract "Objective:To understand the effect of hyperbilirubinemia on neonatal hearing,and explore ABR and TEOAE screening in early finding of auditory neuropathy induced by hyperbilirubinemia by analyzing hearing screening results of neonates with hyperbilirubinemia.Methods:182 neonates with hyperbilirubinemia born from June 2006 to June 2009 were selected and divided into A group and B group,then 546 normal neonates were selected randomly according to 1∶3 as control group;screening-based OAE was used in preliminary screening and secondary screening,then the neonates failing in secondary screening were sent to aural diagnostic center for audiological evaluation and medical diagnosis.Results:A group(serum bilirubin concentration≥342 μmol/L,81 cases)included 53 boys and 28 girls,the failing rate in preliminary screening was 30.86%(25/81),the abnormal rate of ABR was 70.37%(57/81),the definite diagnostic rate of hearing impairment was 28.39%(23/81);11 neonates passing TEOAE preliminary screening and secondary screening,deletion or severe deletion of ABR,high suspicion of auditory neuropathy were subsumed in focus of follow-up.B group(serum bilirubin concentration342 μmol/L,101 cases)included 66 boys and 35 girls,the failing rate in preliminary screening was 17.82%(18/101),the abnormal rate of ABR was 43.56%(44/101),the definite diagnostic rate of hearing impairment was 8.91%(9/101).Control group(serum bilirubin concentration220.6 μmol/L,546 cases)included 317 boys and 229 girls,the failing rate in preliminary screening was 8.79%(48/546),the abnormal rate of ABR was 1.28%(7/546).Conclusion:Hyperbilirubinemia is a high risk factor of neonatal hearing impairment,there is a positive correlation between neonatal bilirubin concentration and the degree of hearing loss.Combined application of ABR and TEOAE is superior to single TEOAE test in early evaluation of neonatal hyperbilirubinemia,especially in children with auditory neuropathy,the former is more accurate and comprehensive." @default.
- W2364706098 created "2016-06-24" @default.
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- W2364706098 date "2010-01-01" @default.
- W2364706098 modified "2023-09-26" @default.
- W2364706098 title "Clinical analysis on hearing screening results of 182 neonates with hyperbilirubinemia" @default.
- W2364706098 hasPublicationYear "2010" @default.
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