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- W2364708128 abstract "Objective To investigate effects of running training on GFAP and GAP-43 expression around infarction area in rats af- ter focal cerebral infarction.Methods 42 healthy male rats were randomly divided into group running(n=18),group resting(n=18),and control group with sham-operated(n=6).The rats in group running were subject to exercise on a treadmill for 30 minutes each day.The rats in group resting were fed without exercise.The rats in control group with sham-operated were just anaesthetized and sliced off scalp. The model of focal cerebral infarction was inducing by photothrombosis of cortical microvessels.The levels of glial fibrillary acidic pro- tein(GFAP)and GAP-43 around the infarct area were observed at 7,14,21days after infarction by using immunohistochemieal staining. Results In group running,expression of GFAP was remarkable increased compared with group resting and control group at 14,21days. The expression of GAP-43 was increased more remarkably in group running than in group resting and control group at 7d,14d.There was no significant difference at 21d among three groups.Conclusions The running training could improve synapse building and new con- tact of synapse by increasing expression of GFAP and GAP-43." @default.
- W2364708128 created "2016-06-24" @default.
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- W2364708128 date "2008-01-01" @default.
- W2364708128 modified "2023-10-07" @default.
- W2364708128 title "Effect of Running Training on GFAP and GAP-43 Expression in Brain of Rats after Focal Cerebral Infarction" @default.
- W2364708128 hasPublicationYear "2008" @default.
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