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- W2364708402 abstract "Objective To determine the change of percentage of CD4~+,CD25~+ regulatory T(Tr),and T lymphocyte subgroups cell on peripheral blood lymphocytes in patients with alopecia areata and its significance. Methods The proportion of peripheral blood CD4~+CD25~+Tr and T lymphocyte subgroups was determined by flow cytometry in 40 patients with severe and local AA respectively.Results The proportion of CD4~+CD25~+Tr in patients with severe AA was lower than that of normal controls(1.43±0.74)% vs(2.25±0.97)%(P0.01),while the proportion of peripheral blood CD4~+T cells(31.42±6.66)% vs(30.69±7.47)%(P0.05)and CD8~+T cells(25.86±4.35)% vs(22.42±6.10)%(P0.01)was higher than that of normal controls,The proportion of CD4~+CD25~+Tr,CD4~+T cells and CD8~+T cells in patients with local AA were(2.14±0.87)%,(32.60±10.27)%和(21.59±5.24)% respectively,without noticeable difference from those of normal controls(P0.05). Conclusion The proportion of CD4~+CD25~+ Tr and CD8~+T cells in peripheral blood lymphocytes patients with AA may indicate the activity of severe AA.It is a feasible method to evaluate the patient's immunological status by measuring the proportion." @default.
- W2364708402 created "2016-06-24" @default.
- W2364708402 creator A5060519673 @default.
- W2364708402 date "2008-01-01" @default.
- W2364708402 modified "2023-09-23" @default.
- W2364708402 title "CD4~+,CD25~+ Regulatory T Cell,and T Lymphocyte Subgroups Detection on Peripheral Blood Lymphocyte and Its' Significance in the Patients with Alopecia Areata" @default.
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