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- W2364729007 abstract "OBJECTIVE To study the effect of menthol and azone on percutaneous permeation of meloxicam from gel.METHODS 0.75% meloxicam gel containing different concentrations of menthol and azone was prepared.The steady state flux of meloxicam from gel was determined in vi tro on excised mouse skin utilizing modified Franz diffusion cells. The accum ulatio n permeation amounts and permeation rate were calculated. RESULTS The meloxicam permeation values (mg/h) ranged from 0.862 without enhancer, to 0 .839,1.973 and 0.967 in the presence of 1%, 3%, 5% menthol, to 0.693, 0 .969, 0.789 in the presence of 1%, 3%, 5% azone, to 1.237, 0.997, 0.9 28 in a combination of 3% menthol and 1%, 3%, 5% azone.CONCLUSION The maximum enhancement was obtained in the meloxicam gel with 3% menthol ." @default.
- W2364729007 created "2016-06-24" @default.
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- W2364729007 date "2005-01-01" @default.
- W2364729007 modified "2023-09-25" @default.
- W2364729007 title "Study on the Permention Agent on Meloxicam Gel" @default.
- W2364729007 hasPublicationYear "2005" @default.
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