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- W2364731230 abstract "Objective To study the concentrations of TNF-α and NO in synovial fluid from patients with knee osteoarthritis(KOA).Methods 59 patients with unilateral KOA were divided into three stages according to clinical examination and X-ray imaging findings in which 18 in early stage,31 in middle stage,and 10 in terminal stage.And 12 healthy volunteers were examined as control.Samples of synovial fluid from all patients and volunteers were collected for measurement of TNF-α and NO.Results The TNF-α and NO levels of synovial fluids in KOA group were significantly higher than the control group(P0.01).With the progress of KOA,the concentrations of TNF-α and NO were increased gradually(P0.01).TNF-α concentration in synovial fluid was correlated positively with NO(r=0.56,P0.05).Conclusion The concentrations of TNF-α and NO in synovial fluids are positively correlated with the lesion degree of KOA,which suggesting TNF-α and NO can be used as biochemical markers for early diagnosis and therapeutic assessment of KOA." @default.
- W2364731230 created "2016-06-24" @default.
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- W2364731230 date "2008-01-01" @default.
- W2364731230 modified "2023-09-23" @default.
- W2364731230 title "The Concentrations of TNF-α and NO in Synovial Fluid of Knee Osteoarthritis Patients" @default.
- W2364731230 hasPublicationYear "2008" @default.
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