Matches in SemOpenAlex for { <https://semopenalex.org/work/W2364734420> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W2364734420 abstract "Objective To investigate the effects of angiotensin Ⅱ type 1 receptor blockade,losartan,on insulin sensitivity and serum lipid in exprerimental fibrotic rats,and to assess the feasibility of the treatment with losartan on insulin resistance in liver cirrhosis.Methods 35 male Wister rats were randomly separated into 3 groups.Excepting 9 rats in control group,13 rats with cirrhosis respectively in model group and treatment group,induced by the compound factors,CCl 4 and high fat feeds,were adopted during the study.After the models succeeded,radioimmunoassay(RIA)was performed to determine the serum level of insulin.The serum levels of glucose and lipid were determined.The histopathologic of liver tissue was examined by optical microscopy.Results Losartan group was compared with the model group:①Decreased serum insulin and glucose and increased insulin sensitivity were dramatic (P0.01);②The serum levels of TG,Ch and HDLC were significantly decreased (P0.01),but LDLC was not significantly reduced (P0.05);③The degree of hepatic fibrosis was ameliorated significantly (P0.01).Conclusion Losartan may be effective in treatment on insulin resistance and glucose and lipid metabolic abnormalities." @default.
- W2364734420 created "2016-06-24" @default.
- W2364734420 creator A5056524939 @default.
- W2364734420 date "2004-01-01" @default.
- W2364734420 modified "2023-09-23" @default.
- W2364734420 title "The study of losartan on insulin resistance in experimental fibrotic rats" @default.
- W2364734420 hasPublicationYear "2004" @default.
- W2364734420 type Work @default.
- W2364734420 sameAs 2364734420 @default.
- W2364734420 citedByCount "0" @default.
- W2364734420 crossrefType "journal-article" @default.
- W2364734420 hasAuthorship W2364734420A5056524939 @default.
- W2364734420 hasConcept C126322002 @default.
- W2364734420 hasConcept C134018914 @default.
- W2364734420 hasConcept C170493617 @default.
- W2364734420 hasConcept C176685330 @default.
- W2364734420 hasConcept C2777214474 @default.
- W2364734420 hasConcept C2777391703 @default.
- W2364734420 hasConcept C2778163477 @default.
- W2364734420 hasConcept C2778270857 @default.
- W2364734420 hasConcept C2779306644 @default.
- W2364734420 hasConcept C2780288358 @default.
- W2364734420 hasConcept C2780559512 @default.
- W2364734420 hasConcept C2908929049 @default.
- W2364734420 hasConcept C71924100 @default.
- W2364734420 hasConceptScore W2364734420C126322002 @default.
- W2364734420 hasConceptScore W2364734420C134018914 @default.
- W2364734420 hasConceptScore W2364734420C170493617 @default.
- W2364734420 hasConceptScore W2364734420C176685330 @default.
- W2364734420 hasConceptScore W2364734420C2777214474 @default.
- W2364734420 hasConceptScore W2364734420C2777391703 @default.
- W2364734420 hasConceptScore W2364734420C2778163477 @default.
- W2364734420 hasConceptScore W2364734420C2778270857 @default.
- W2364734420 hasConceptScore W2364734420C2779306644 @default.
- W2364734420 hasConceptScore W2364734420C2780288358 @default.
- W2364734420 hasConceptScore W2364734420C2780559512 @default.
- W2364734420 hasConceptScore W2364734420C2908929049 @default.
- W2364734420 hasConceptScore W2364734420C71924100 @default.
- W2364734420 hasOpenAccess W2364734420 @default.
- W2364734420 hasRelatedWork W2001416642 @default.
- W2364734420 hasRelatedWork W2015836575 @default.
- W2364734420 hasRelatedWork W2049998205 @default.
- W2364734420 hasRelatedWork W2186043199 @default.
- W2364734420 hasRelatedWork W2323032905 @default.
- W2364734420 hasRelatedWork W2347490708 @default.
- W2364734420 hasRelatedWork W2348729632 @default.
- W2364734420 hasRelatedWork W2348915514 @default.
- W2364734420 hasRelatedWork W2354366339 @default.
- W2364734420 hasRelatedWork W2364916022 @default.
- W2364734420 hasRelatedWork W2372166006 @default.
- W2364734420 hasRelatedWork W2373778099 @default.
- W2364734420 hasRelatedWork W2385364025 @default.
- W2364734420 hasRelatedWork W2387683884 @default.
- W2364734420 hasRelatedWork W2388187404 @default.
- W2364734420 hasRelatedWork W2507807596 @default.
- W2364734420 hasRelatedWork W2736569586 @default.
- W2364734420 hasRelatedWork W2809658305 @default.
- W2364734420 hasRelatedWork W2982264038 @default.
- W2364734420 hasRelatedWork W3167311867 @default.
- W2364734420 isParatext "false" @default.
- W2364734420 isRetracted "false" @default.
- W2364734420 magId "2364734420" @default.
- W2364734420 workType "article" @default.