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- W2364734434 abstract "Objective:To evaluate the effect and sanfety of irinotecan versus oxaplatin combination with 5-FU/CF for patients with advanced colorectal cancer.Methods:Articles on the two systemic chemotherapy for advanced colorectal cancer published in 2000—2008 were retrieved using the Keywords:colorectal cancer,chemotherapy,irinotecanoroxaplatinfromVip Chinese Science and Technology Periodicals database, then the whole text was read to get all-related information.The data were descriptively analyzed.Results:There were 283 articles on irinotecan versus oxaplatin combination with 5-FU/CF for patients with colorectal Cancer, 16 of which on FOLFIRI were included while 96 of which on FOLFOX. Among the articles statistically studied, median survival time were reported in 33, time of tumor progress in 30.The response rate of FOLFOX4, FOLFOX6, and other oxaliplatin-related regimens was 26.1%~57.14%, 33.3%~48.6%, and26.5%~60%, respectively.The response rate of FOLFIRI was 12.5%~48.2%. Conclusion: The effect of FOLFIRI or FOLFIRI for advanced colorectal cancer are in agreement with those reported abroad.However, there ara certain shortcomings in the application of regimens and the design of domestic clinical studies,thus affecting the results of studies." @default.
- W2364734434 created "2016-06-24" @default.
- W2364734434 creator A5042437367 @default.
- W2364734434 date "2010-01-01" @default.
- W2364734434 modified "2023-09-23" @default.
- W2364734434 title "Chinese Reports on the Effect and Safety of FOLFOX or FOLFIRI for Advanced Colorectal Cancer" @default.
- W2364734434 hasPublicationYear "2010" @default.
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