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- W2364739907 abstract "To synthesize eudistomin U and its 6-OCH3/Br derivatives and 5'-Br derivatives as antitumor agents.Using tryptamine and indole-3-aldehyde as starting materials, through condensation, Pictet-Spengler cyclization and dehydrogenation three steps, the alkaloids and its derivatives were prepared.The structures of the compounds were determined by 1HNMR, MS and HRMS. Antitumor activity in vitro was tested.Eudistomin U and its derivatives were synthesized. The results showed that they all showed antitumor activities against mouse P388 strain." @default.
- W2364739907 created "2016-06-24" @default.
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- W2364739907 date "2004-04-01" @default.
- W2364739907 modified "2023-09-23" @default.
- W2364739907 title "[Synthesis of 1-indole substituted beta-carboline alkaloid and its derivatives and evaluation of their preliminary antitumor activities]." @default.
- W2364739907 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15303653" @default.
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