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- W2364741107 abstract "Objective To assess the clinical efficacy of the α1 blocker—tamsulosin in the medical-expulsive therepy of distal ureterolithiasis.Methods A total of 203 patients with stones located in the lower ureter(juxtavesical or intramural tract) were enrolled in the study and were randowly divided into 2 groups.Group-1(100)patients received daily oral treatment of Jingshiling Jiaonang(1.5Tid/day),Group-2 received daily oral treatment of tamsulosin(0.4mg/day).The treatment period was 28 days for both groups.Statistical analyses were performed using independent-Samples T Test、chi-square Test、Cox Regression model and independent Logistic Regression.Results Expulsion was observed in 62 of 100 patients in group-1(62%),82 of 103 in group-2(79.6%).The difference in group-1 with respect to group-2 was significant.Average expulsion time for group-1 and group-2was 10.8 days and 8.51 days.A statistical significant difference was noted in the two grouops.In the treatment time,there was not significant difference in the two groups with ER visits and Urgent hospitalization、workdays lost and durg side effects.The QOL of two groups have not significant difference,but the average value of group-2 was lower than group-1.Conclusion The results of this study indicate that lower tract ureteral stones can be treated with an expulsive medical therapy in patients when a watchful waiting approach is possible.In our study medical treatments with tamsulosin proved to be safe and effective as demonstrated by the low incidence of side effects and the increased stone expulsion rate and reduce expulsion times." @default.
- W2364741107 created "2016-06-24" @default.
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- W2364741107 date "2010-01-01" @default.
- W2364741107 modified "2023-09-22" @default.
- W2364741107 title "The Clinic Randomized Research of the Medical-expulsive Therapy for Distal Ureterolithiasis Used with Tamsulosin" @default.
- W2364741107 hasPublicationYear "2010" @default.
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