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- W2364744541 abstract "Objective To investigate p53 expression in non-small cell lung cancer,and its relationships with clinical characteristics and chemoradiotherapy efficacy. Methods Immunohistochemistry was used to detect the expression of p53 in 100 cases of non-small cell lung cancer tissues,and the expression strength was detected using micro image analyzer. The relationships between p53 expression and clinical characteristics and chemo-radiotherapy efficacy were analyzed. Results The positive rate of p53 in non-small cell lung cancer was 48%; there were no correlations among p53 expression and lymph node metastasis,distant metastasis or TNM stage; NSCLC patients with p53 expression had worse chemo-radiotherapy effect than those without p53 expression,and p53 expression was negatively associated with patients' survival time. Conclusion The status of p53 expression have effect on synchronous chemotherapy in patients with non-small cell lung cancer,and is directly related with the survival time. p53 may be represented as a promising target for non-small cell lung cancer." @default.
- W2364744541 created "2016-06-24" @default.
- W2364744541 creator A5032419860 @default.
- W2364744541 date "2016-01-01" @default.
- W2364744541 modified "2023-09-27" @default.
- W2364744541 title "The Correlations between p53 Expression and Clinical Characteristics and Chemo-radiotherapy Efficacy in Non-small Cell Lung Cancer" @default.
- W2364744541 hasPublicationYear "2016" @default.
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