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- W2364754154 abstract "Objective:To study the effect of letrozole on sexual hormones during luteal phase among the high risk patients of ovarian hyperstimulation syndrome(OHSS) after oocyte retrieval and its preventive effect on OHSS.Methods:A total of 196 in vitro fertilization(IVF)/intracytoplasmic sperm injection(ICSI) cycles(193 high risk patients of OHSS) were prepared for embryo cryopreservation after oocyte retrieval,then they were divided into experiment group and control according to adding letrozole or not after oocyte retrieval,the patients in experiment group were treated with oral administration of letrozole after oocyte retrieval,while the patients in control were not treated with letrozole.The levels of luteinizing hormone(LH),estradiol,and progestogen,the incidences of moderate and severe OHSS on the day of human chorionic gonadotropin(HCG) injection,the second,the fourth,and the ninth days after HCG injection in the two groups were compared.Results:There was no significant difference in the levels of LH,estradiol,and progestogen on the second day after HCG injection,the levels of LH and progestogen on the fourth day and the ninth day after HCG injection between the two groups(P0.05).The levels of estradiol,the incidences of moderate and severe OHSS on the fourth day and the ninth day after HCG injection in experiment group were significantly lower than those in control group(P0.01).Conclusion:Providing letrozole for the high risk patients of OHSS after oocyte retrieval can reduce the level of estradiol during luteal phase and the incidences of moderate and severe OHSS effectively." @default.
- W2364754154 created "2016-06-24" @default.
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- W2364754154 date "2012-01-01" @default.
- W2364754154 modified "2023-09-25" @default.
- W2364754154 title "Application of letrozole in decrease of estrogen level and the incidence of OHSS during luteal phase after oocyte retrieval" @default.
- W2364754154 hasPublicationYear "2012" @default.
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