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- W2364757551 abstract "Objective To investigate the impact of aging on complex fractionated atiral electrograms( CFAEs) in patients with non-valvular chronic atrial fibrillation( AF). Methods In this prospective study,116 patients with chronic AF were enrolled( n = 48 in the elderly group,n = 68 in the non elderly group). The elderly was defined as age ≥ 60 years old. The 2. 5-second bipolar electrogram recordings at each endocardial location were analyzed with a custom software embedded in the CARTO mapping system. Interval confidence level( ICL) was used to characterize CFAEs. As the default setting of the software,ICL more than or equal to 7 was considered sites with a highly repetitive CFAEs complex. CFAEs index was defined as the fraction of area of ICL more than or equal to 7 to the left atrial surface. The spatial distribution of CFAEs evaluated in six left atrial( LA) regions: anterior wall,posterior wall,roof,inferior wall,lateral wall and septum.Results The elderly group had higher prevalence of male,hypertension and stroke( all P0. 05). ICL max [( 16. 7±2.0) vs( 15. 7±2. 2),P = 0. 014]and CFAEs index [( 60. 4% ±22. 9%) vs( 48. 6% ±22. 3%),P = 0. 007]in the elderly group was significantly higher than that in the non-elderly group. The regional distribution of CFAEs was frequently found in Conclusion LA anterior wall and LA septum in the elderly. Age had positive relation with CFAEs( r = 0. 244,P = 0. 008). The elderly have extensive substrate for chronic AF." @default.
- W2364757551 created "2016-06-24" @default.
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- W2364757551 date "2014-01-01" @default.
- W2364757551 modified "2023-09-26" @default.
- W2364757551 title "Aging and complex fractionated atrial electrograms in patients with chronic atrial fibrillation" @default.
- W2364757551 hasPublicationYear "2014" @default.
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