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- W2364762235 abstract "Objective To investigate the immunophenotype characteristics of hyperleukocytic acute leukemia and to analyze its clinical feature.Methods Immunophenotyping was performed in 48 HLAL and 189 NHLAL patients by flow cytometry and its clinical feature has been analyzed.Results The results showed that as compared with NHLAL group,the clinical progress of HLAL was faster,the CR rate was lower(P0.05),the infiltration was obvious,the proliferation of bone marrow was more active(P﹤0.05).The cross expressing positive rate of different lineage associated antigens was higher in HLALL group.The positive rate of CD7 expression was same in 4 groups.The positive rate of CD33 and CD13 was higher in HLAML and NHLAML group.Conclusion As compared with NHLAL,the clinical progress of HLAL was faster,the proliferation of bone marrow was more active,the treatment was more difficult.HLALL has high heterogeneity.The positive expression of CD7 has not specificity.CD33 and CD13 is more reliable to be myeloid-specific antigen." @default.
- W2364762235 created "2016-06-24" @default.
- W2364762235 creator A5058394781 @default.
- W2364762235 date "2012-01-01" @default.
- W2364762235 modified "2023-09-27" @default.
- W2364762235 title "A research for immunophenotype characteristics and clinical feature of hyperleukocytic acute leukemia" @default.
- W2364762235 hasPublicationYear "2012" @default.
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