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- W2364763356 abstract "Objective To explore the efficacy and safety of aripiprazole in the treatment of childhood or adolescent with schizophrenia.Methods Patients who met CCMD-3 criteria for schizophrenia were randomized into two groups:aripiprazole group(n=35)and haloperidol group(n=32)in control study.The treatment duration was 8 weeks.The PANSS and BRPS were employed for assessing the treatment effectiveness.The TESS and RSESE were employed for assessing the side effects.Results The score of PANSS and BPRS of both groups significantly dropped after treatment(P0.01).Aripiprazole group for the efficient 68.57%;Haloperidol group for 65.63% is efficient,the aripiprazole group and haloperidol group is no marked difference in effect(P0.05).Two groups in treating the negative symptoms for 4.8 weeks have a significant gender difference(P0.05).The score of aripiprazole group below haloperidol group.The side effects of aripiprazole group is insomnia,headache,anxiety or abnormal response and haloperidol group is somnolence,myotonia,akathisia or tremor.The both groups have a significant gender difference(P0.01).Conclusion Aripiprazole is effective in treatment childhood or adolescent with schizophrenia who have positive or negative symptom and with few side effects.Aripiprazole is more suited to patients who cannot tolerance the extrapyrramidal system reaction." @default.
- W2364763356 created "2016-06-24" @default.
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- W2364763356 date "2011-01-01" @default.
- W2364763356 modified "2023-09-24" @default.
- W2364763356 title "A controlled study of aripiprazole and haloperidol in the treatment of childhood or adolescent with schizophrenia" @default.
- W2364763356 hasPublicationYear "2011" @default.
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