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- W2364774652 abstract "Objective:To investigate the significance of CD 44v6 and p27 protein expression in colorectal adenocarcinoma.Methods:The expression of CD 44v6 and p27 protein was examined with immunohistochemical S P method.Results:The total positive rates of CD 44v6 and p27 protein staining in 60 cases of colorectal adenocacinomn were 57 % (34/60) and 22 % (13/60),respectively.They were not evidently correlated with histological differentiation and depth of tumor invasion ( P 0.05),but the expression of CD 44v6 and p27 protein was corelated with lymphnode metastasis and prognosis of colorectal carcinoma ( P 0.05).The positive expression of CD 44v6 was positively corelated with lymphnode metastasis of colorectal carcinoma, but had a inverse correlation with prognosis of rectal carcinoma.The positive expression of p27 had the contrary result with CD 44v6 positive expression.Conclusion:The positive expression of CD 44v6 and p27 protein was correlated with matastasis and prognosis of rectal carcinoma. Detecting the expressive levels of CD 44v6 and p27 protein have certain referent values for judging the malignant degree, potentials of reccurrence, metastasis of rectal carcinoma ,evaluating prognosis of patients and selecting the rational therapeutic protocol after surgery." @default.
- W2364774652 created "2016-06-24" @default.
- W2364774652 creator A5067234314 @default.
- W2364774652 date "2003-01-01" @default.
- W2364774652 modified "2023-09-27" @default.
- W2364774652 title "SIGNIFICANCE OF CD_(44v6) AND p27 PROTEIN EXPRESSION IN COLORECTAL ADENOCARCINOMA" @default.
- W2364774652 hasPublicationYear "2003" @default.
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