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- W2364776301 abstract "Objective To study the antitumor activity of noviose and coumarin in novobiocin. Methods Synthesis 3-O-carbamylnoviose and 3-acetamido-7-hydroxycoumarin,compare the activity of inhibit K562 cell with novobiocin by MTT. Results The half maximal inhibitory concentration(IC50): compound 2 was 2.287 mmol/L,compound 3 was 2.165 mmol/L,novobiocin was 0.350 mmol/L. Conclusion Noviose and coumarin have a little antitumor activity but it is weaker than novobiocin." @default.
- W2364776301 created "2016-06-24" @default.
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- W2364776301 date "2008-01-01" @default.
- W2364776301 modified "2023-09-23" @default.
- W2364776301 title "Synthesis the Structure Unit in Novobiocin and Study Antitumor Activity" @default.
- W2364776301 hasPublicationYear "2008" @default.
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