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- W2364791503 abstract "Objective:To investigate the effect of Yangxintongmaifang(YX)on hemorheology and platelet aggregation in rats.Methods:SD rats were randomly divided into 0.9%Nacl group,Aspirin group,low doses YX decoction group and high doses YX decoction group.Blood samples were collected 3 days after administeration.The whole blood viscosity was assayed with rotational viscometer.Hematocrit was assayed with wintrobe method.Platelet aggregation was assayed with turbidirmetry.Results:Each group had a significent improvement in the whole blood viscosity and hematocrit in rats(P0.05-0.001)and the effect of the YX group was in a dose-dependent manner.Improvement of the whole blood viscosity at low shear rat in the YX group was superior to that in the Aspirin group.There was a significant suppression to the platelet aggregation in rats induced by ADP by treating in vivo with YX,the effect of the high dosie YX group was found equal to that of the Aspirin group.Conclusion:Yangxintongmaifang can obviously improve the hemorheology and platelet aggregation in rats.The effect may be one of the definite effect's mechanisms in treating CHF." @default.
- W2364791503 created "2016-06-24" @default.
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- W2364791503 date "2008-01-01" @default.
- W2364791503 modified "2023-10-17" @default.
- W2364791503 title "The Effect of Yangxintongmaifang on Hemorheology and Platelet Aggregation in Rats" @default.
- W2364791503 hasPublicationYear "2008" @default.
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