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- W2364793105 abstract "Objective: To investigate the expression and significance of Twist in thymic epithelial tumor.Methods: We immuno-histochemically investigated the relation between the expression and clinicopathological factors including prognsis in surgical specimens of thymic epithelial tumor in 87 patients including 71 patients with thymomas and 16 specimens of thymic carcinoma.Results: Among the 71 thymomas,8(11.3%) cases were positive for Twist immunoexpression,and 13(81.3%) cases were positive in 16 thymic carcinoma.The expression of Twist was significantly higher in thymic carcinoma than in thymomas(P0.001).The expression of Twist among sub-types of thymomas(A,AB,B1,B2,B3) is not statistically different(P0.005).The Twist expression was positively related with distant metastasis after operation(r=0.40,P=0.001).Kaplan-Meier analysis showed that the positive expression of Twist was significantly associ-ated with lower survival rates of patients after operation(P0.001).Conclusion: Evaluation of Twist expression may have significant reference value to distinguish between thymomas and thymic carcinoma.The positive expression of Twist should be associated with the metastasis and survival in postoperative." @default.
- W2364793105 created "2016-06-24" @default.
- W2364793105 creator A5027262387 @default.
- W2364793105 date "2012-01-01" @default.
- W2364793105 modified "2023-09-23" @default.
- W2364793105 title "Significance of Twist Expression in Thymic Epithelial Tumor" @default.
- W2364793105 hasPublicationYear "2012" @default.
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