Matches in SemOpenAlex for { <https://semopenalex.org/work/W2364800858> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2364800858 abstract "Objective To investigate the apoptosis of alveolar macrophage and its significance in patients with chronic obstructive pulmonary disease (COPD). Methods A total of 11 patients with COPD and 10 healthy controls were enrolled in the study. Alveolar macrophages (AM) were harvested from the BALF (bronchoalveolar lavage fluid). The positive rate of myeloperoxidase (MPO) staining of alveolar macrophages by MPO staining was observed so as to indirectly reflect neutrophil apoptosis and the phagocytosis of apoptotic neutrophils by alveolar macrophages. Apoptosis were detected by the transferase-mediated dUTP nick end labeling (TUNEL) technique. Results The positive rate of alveolar macrophages by MPO staining was lower in COPD group than the control group (P0.01). The apoptotic rate of macrophages within BALF from COPD group was much lower than the control group[(1.9±0.7)% vs (4.8±1.3)%] (P0.01). DEX induced the apoptosis of cultured alveolar macrophages in a time-dependent manner and the apoptotic rate of AM treated with DEX for 12, 24, 48 h in COPD group was higher than the control group. Conclusion There was a decreased apoptosis of alveolar macrophages and a less phagocytosis of apoptotic neutrophil by alveolar macrophages in patients with COPD. DEX can significantly induce the apoptosis of alveolar macrophages." @default.
- W2364800858 created "2016-06-24" @default.
- W2364800858 creator A5029678331 @default.
- W2364800858 creator A5045073296 @default.
- W2364800858 creator A5048959337 @default.
- W2364800858 date "2005-01-01" @default.
- W2364800858 modified "2023-09-22" @default.
- W2364800858 title "Detection of alveolar macrophage apoptosis in patients with chronic obstructive pulmonary disease" @default.
- W2364800858 hasPublicationYear "2005" @default.
- W2364800858 type Work @default.
- W2364800858 sameAs 2364800858 @default.
- W2364800858 citedByCount "0" @default.
- W2364800858 crossrefType "journal-article" @default.
- W2364800858 hasAuthorship W2364800858A5029678331 @default.
- W2364800858 hasAuthorship W2364800858A5045073296 @default.
- W2364800858 hasAuthorship W2364800858A5048959337 @default.
- W2364800858 hasConcept C126322002 @default.
- W2364800858 hasConcept C142724271 @default.
- W2364800858 hasConcept C154113507 @default.
- W2364800858 hasConcept C160448771 @default.
- W2364800858 hasConcept C185592680 @default.
- W2364800858 hasConcept C190283241 @default.
- W2364800858 hasConcept C196795494 @default.
- W2364800858 hasConcept C202751555 @default.
- W2364800858 hasConcept C203014093 @default.
- W2364800858 hasConcept C203565725 @default.
- W2364800858 hasConcept C204232928 @default.
- W2364800858 hasConcept C2776178081 @default.
- W2364800858 hasConcept C2776780178 @default.
- W2364800858 hasConcept C2776914184 @default.
- W2364800858 hasConcept C2777714996 @default.
- W2364800858 hasConcept C2777961210 @default.
- W2364800858 hasConcept C2778012055 @default.
- W2364800858 hasConcept C2778543330 @default.
- W2364800858 hasConcept C2779244956 @default.
- W2364800858 hasConcept C55493867 @default.
- W2364800858 hasConcept C71924100 @default.
- W2364800858 hasConceptScore W2364800858C126322002 @default.
- W2364800858 hasConceptScore W2364800858C142724271 @default.
- W2364800858 hasConceptScore W2364800858C154113507 @default.
- W2364800858 hasConceptScore W2364800858C160448771 @default.
- W2364800858 hasConceptScore W2364800858C185592680 @default.
- W2364800858 hasConceptScore W2364800858C190283241 @default.
- W2364800858 hasConceptScore W2364800858C196795494 @default.
- W2364800858 hasConceptScore W2364800858C202751555 @default.
- W2364800858 hasConceptScore W2364800858C203014093 @default.
- W2364800858 hasConceptScore W2364800858C203565725 @default.
- W2364800858 hasConceptScore W2364800858C204232928 @default.
- W2364800858 hasConceptScore W2364800858C2776178081 @default.
- W2364800858 hasConceptScore W2364800858C2776780178 @default.
- W2364800858 hasConceptScore W2364800858C2776914184 @default.
- W2364800858 hasConceptScore W2364800858C2777714996 @default.
- W2364800858 hasConceptScore W2364800858C2777961210 @default.
- W2364800858 hasConceptScore W2364800858C2778012055 @default.
- W2364800858 hasConceptScore W2364800858C2778543330 @default.
- W2364800858 hasConceptScore W2364800858C2779244956 @default.
- W2364800858 hasConceptScore W2364800858C55493867 @default.
- W2364800858 hasConceptScore W2364800858C71924100 @default.
- W2364800858 hasLocation W23648008581 @default.
- W2364800858 hasOpenAccess W2364800858 @default.
- W2364800858 hasPrimaryLocation W23648008581 @default.
- W2364800858 hasRelatedWork W1972872876 @default.
- W2364800858 hasRelatedWork W1980191732 @default.
- W2364800858 hasRelatedWork W2021629309 @default.
- W2364800858 hasRelatedWork W2038665431 @default.
- W2364800858 hasRelatedWork W2057350577 @default.
- W2364800858 hasRelatedWork W2060646210 @default.
- W2364800858 hasRelatedWork W2086894586 @default.
- W2364800858 hasRelatedWork W2092503695 @default.
- W2364800858 hasRelatedWork W2112361453 @default.
- W2364800858 hasRelatedWork W2118134981 @default.
- W2364800858 hasRelatedWork W2123440696 @default.
- W2364800858 hasRelatedWork W2364990179 @default.
- W2364800858 hasRelatedWork W2369831248 @default.
- W2364800858 hasRelatedWork W2411653997 @default.
- W2364800858 hasRelatedWork W2469840724 @default.
- W2364800858 hasRelatedWork W2511955406 @default.
- W2364800858 hasRelatedWork W2742088396 @default.
- W2364800858 hasRelatedWork W3008537494 @default.
- W2364800858 hasRelatedWork W3031063950 @default.
- W2364800858 hasRelatedWork W3107701155 @default.
- W2364800858 isParatext "false" @default.
- W2364800858 isRetracted "false" @default.
- W2364800858 magId "2364800858" @default.
- W2364800858 workType "article" @default.