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- W2364823043 abstract "Objective To investigate the value of perfusion CT(PCT) on the experi mental subarachnoid hemorrhage(SAH) in r abbit.Methods The rabbits receiv ed two subarachnoid injections of autolo gous art erial blood(1ml/kg)to induce SAH.PCT wa s used on the 1st,3rd,7th and 14th day.Re gional cerebral blood flow(rCBF),regiona l cerebral blood volume(rCBV),time to pe ak(TTP) were measured based on the S-T c urve.HE staining was performed for path ology. Results rCBF,rCBV and TTP in nor ma l rabbits were(142.283±9.749)ml·min~-1· 10 0g~-1,(247.517±37.920)ml·min~-1·100g~- 1 and (3.383±0.194)s respectively.rCBF clearl y decreased as early as on the 3rd day a fter SAH [(62.583±5.123)ml·min~-1·100g~ -1] ,increased on the 7th day, but was still abnormal on the 14th day.rCBV decreased markedly on the 3rd day and increased on the 7th day,then came back.TTP was prol onged on the 3rd day.Denaturalization wa s observed pathologically in regional b rain, and more obviously on the 7th day a fter SAH. Conclusion PCT is a convenient and effective technique for evaluating h emodynamics after SAH.Analyzing the rela tionship of rCBF,rCBV,and TTP is helpful to know the status of the capillary ves sels in the brain and can provide functio nal information.It also provides the clues i ndicating the exist of ischemia and the g r ade." @default.
- W2364823043 created "2016-06-24" @default.
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- W2364823043 date "2005-01-01" @default.
- W2364823043 modified "2023-09-22" @default.
- W2364823043 title "Changes of cerebral blood flow with perfusion CT after experimental subarachnoid hemorrhage in rabbits" @default.
- W2364823043 hasPublicationYear "2005" @default.
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