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- W2364843946 abstract "Objective:To investigate the influence of Jiangu Decoction (JGD) on cancellous bone in senile orchiectomized (ORX) rats via bone mineral density (BMD) test,bone biomechanical analysis,micro-CT scanning and three-dimensional structure reconstruction. Methods:Thirty 12-month-old male Wister rats were randomly divided into ORX group,sham-operated group (Sham group) and ORX+JGD group,10 rats in each group. Rats in Sham group and ORX group received intragastric administration of 0.9% NaCl daily while rats in ORX+JD group received JGD extract (5ml/kg/d) for 12 weeks. Dual energy X-ray absorptiometry was used to measure total body BMD,micro-CT scanning and three-dimensional structure reconstruction were used to analyze right femurs and L-3 vertebra,and bone biomechanical test was carried on left femurs and L-4 vertebra. Results:Compared with ORX group,the following indexes in ORX+JGD all significantly increased:BMD,the volume,thickness and number of trabecular bone,maximum load,energy absorption,maximum stress and elastic modulous. Meanwhile,the space of trabecular bone and structure model index all decreased. Conclusion:Jiangu Decoction could prevent the bone loss,increase micro-architecture and biomechanical properties of the trabecular bone in ORX rats." @default.
- W2364843946 created "2016-06-24" @default.
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- W2364843946 date "2008-01-01" @default.
- W2364843946 modified "2023-09-26" @default.
- W2364843946 title "The Influence of Jiangu Decoction on Cancellous Bone in Rats after Orchiectomy" @default.
- W2364843946 hasPublicationYear "2008" @default.
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