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- W2364844522 abstract "Accumulated evidence supports that there are distinct structural and functional changes in age-related enteric neurodegeneration,which are characterized by selective loss of enteric cholinergic neurons,damage of enteric nitrergic fiber,axonopathy in sympathetic nerves and neurotransmitters changes.Because of these reasons,the neuro-muscular activity of gastrointestinal (GI) tract was affected.Recent researches demonstrated that enteric neurodegeneration should be associated with a direct alpha-synuclein-positive route for transynaptic retrograde transport from gut to brain.To understand these pathological characters and to provide scientific evidences for prevention and treatment of age-related disorder in GI,this article reviewed the recent data about enteric neurodegeneration in ageing." @default.
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- W2364844522 date "2009-01-01" @default.
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- W2364844522 title "Enteric Neurodegeneration in Ageing" @default.
- W2364844522 hasPublicationYear "2009" @default.
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