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- W2364846875 abstract "Objective: To investigate the relationship of mdm2 protein expression with pathological types and recurrence in patients with GCT of bone. Methods: Expression levels of mdm2 proteins in 52 cases of patients with GCT were examined immunohistochemically,using anti-mdm2 proteins monoclonal antibodies. Results: 18 of 52 tumors expressed mdm2 protein.40.0% of the gradeⅠ,32.0% of the gradeⅡ and 33.3% of the grade Ⅲ giant cell tumor of bone showed mdm2 protein positive. Positivity for mdm2 were found in 75.0%(6/8)of the recurrence cases and 27.3%(12/44) of the no recurrence cases. A positive relationship exists between the recurrence and mdm2 protein positivity (P0.01). However, there was no association between mdm2 positivity and pathological types. Conclusion: There was a statistically significant correlation between the expression of mdm2 protein in the giant cell tumor of bone and the recurrence." @default.
- W2364846875 created "2016-06-24" @default.
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- W2364846875 date "2000-01-01" @default.
- W2364846875 modified "2023-09-24" @default.
- W2364846875 title "Expression of mdm2 Protein in Human Giant Cell Tumors of Bone with Recurrence" @default.
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