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- W2364850255 abstract "Objective:To study the effects of Xuefuzhuyu extractive in acute bacterial peritonitis rats on the concentration of endotoxin in plasma and the bacteria translocation with mesenteric lympha node and liver.Methods 40 Sprague-Dawley rats were intraperitoneally injected with Escherichia coli.to induce acute bacterial peritonitis;meanwhile,Xuefuzhuyu extractive water-solution of 10、15 and 20 times the adult dosage was intragastricly given to the low(L)、medium(M)、high(H) therapeutic groups individually.After 66 hours,blood was collected from angular venous plexus and kept for measuring endotoxin with LAL(Limulus Amebocyte Lysate).After 72 hours,all animals were sacrificed,tissues were sterily collected for measuring the bacteria translocation with mesenteric lympha node and liver with the mothod of bacterial culture.Results The concentration of endotoxin in therapeutic groups was lower than model control(C)group(P0.01);the bacteria translocation with liver in L group is lower than C group;there was no significant difference between C group and therapeutic groups in the bacteria translocation with mesenteric lympha node.Conclusion The Xuefuzhuyu extractive can play an important role in reducing the concentration of endotoxin in plasma and decreasing the incidence of bacterial translocation with liver." @default.
- W2364850255 created "2016-06-24" @default.
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- W2364850255 date "2010-01-01" @default.
- W2364850255 modified "2023-09-25" @default.
- W2364850255 title "Effects of Xuefuzhuyu Extractive in Acute Bacterial Peritonitis Rats on Concentration of Endotoxin in Plasma and Bacteria Translocation" @default.
- W2364850255 hasPublicationYear "2010" @default.
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