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- W2364854920 abstract "Objective To study the mutagenic effect of nicosulfuron and predict its potential genetic and carcinogenic effect. Methods Kunming mice were gavaged nicosulfuron (the dose for chromosome aberration of bone marrow was 250,500 and 1 000 mg/ kg, the dose for testes' chromosome was 300,1 500 and 3 000 mg/kg). Chromosome sections from femora and testes were prepared with routine method, median-phase chromosome were observed. Ames Salmoonella/microsome plate assay were used. The dose of Ames test was 0.032, 0.16, 0.8, 4.0 ug/plate. Results Chromosome aberration of bone marrow and testes of mice indicated that the nicosulfuron group did not show significant difference from the negative control group ( P 0.05) . Ames test showed that nicosulfuron group didn t cause double increase of revertants at all doses in every bacterial strains. Conclusion Nicosulfuron might have no mutagenic effect in this study." @default.
- W2364854920 created "2016-06-24" @default.
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- W2364854920 date "2003-01-01" @default.
- W2364854920 modified "2023-09-28" @default.
- W2364854920 title "The mutagenic study of nicosulfuron" @default.
- W2364854920 hasPublicationYear "2003" @default.
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