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- W2364867575 abstract "Objective To analyze the mechanical properties of iris tissue based on stimulating pupillary blocking force in order to find the relation between the parameter of the iris property and the differential pressure between the anterior and posterior chamber.Methods We applied simulating pupillary blocking device to simulate the pupillary blocking force and used liquid loading apparatus to simulate the differential pressure between the anterior and posterior chamber.Then we loaded pressure on the integrative iris to quantitatively analyze the relationship between the pressure of the anterior and posterior chamber with the change of the strain of iris surface and the radius of iris curvature under the pupillary blocking force.Results The model was similar with the clinical phenomena.This model was more true to nature than the model that we sutured the pupil before.Using the model,we gained the equation containing the strain of iris surface(δ),the radius of iris curvature(r) and the differential pressure between the anterior and posterior chamber(ΔP).The equation of δ and ΔP was ΔP=b_0e~ b_1δ (b_0=3.337 3,b_1= 30.390 9 ).The equation of r and ΔP was r=e~ (b_0+b_1/ΔP) (b_0=0.476 1,b_1= 21.660 43 ).We realized the quantitative analysis and described the relationship between the different pupillary blocking force and the differential pressure between the anterior and posterior chamber.Conclusion We realize the quantitative measurement for small dynamic parameter of soft tissue.The strain of surface and the radius of curvature of the iris is the property parameter that can be measured.They can reflect the change of the differential pressure between the anterior and posterior chamber sensitively.The radius of curvature of the highest spot of the iris can be measured easily in clinic.So it can help us diagnose and treat the glaucoma early." @default.
- W2364867575 created "2016-06-24" @default.
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- W2364867575 date "2006-01-01" @default.
- W2364867575 modified "2023-09-23" @default.
- W2364867575 title "An experiment research based on simulating pupillary blocking force to analyze mechanical properties of iris tissue quantitatively" @default.
- W2364867575 hasPublicationYear "2006" @default.
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