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- W2364873318 abstract "Objective To study the effects of the serum resistin,leptin and TNF-α on ischemia/reperfusion rat with diabetes mellitus(DM).Methods The DM rats models were mad by injecting streptozotocin into abdominal cavity,ischemia/reperfusion rats models were made by middle cerebral artery occlusion with thread.Serum insulin and resistin were detected by ELISA.Results The level of serum TNF-α,leptin and resistin in DM group is higher than that in the controlled group,and heightened significantly in ischemia/reperfusion group,but the level of serum resistin decreases in ischemia/reperfusion group.Conclusions The serum and resisitin play an important part in process of ischemia/reperfusion,but TNF-α can negatively regulate resistin.The interaction between TNF-α and leptin lead to leptin resistance,and makes serum leptin decrease." @default.
- W2364873318 created "2016-06-24" @default.
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- W2364873318 date "2007-01-01" @default.
- W2364873318 modified "2023-09-22" @default.
- W2364873318 title "Effects of resistin,leptin and TNF-α in ischemia/reperfusion rat with diabetes mellitus" @default.
- W2364873318 hasPublicationYear "2007" @default.
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