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- W2364891336 abstract "Objective To explore the blood concentration of theophylline in patients with acute exacerbation of chronic obstructive pulmonary disease(COPD),and to provide reference for clinical medication.Methods The steady state trough concentration of theophylline was determined by high performance liquid chromatography.The relationships among the blood concentration,the effect and the adverse drug reaction were analyzed.Results There had 5 adverse drug reactions in 132 cases.The results of blood concentration of theophylline were as follows: 35 cases 5 μg/ml with effective rate of 85.7%;64 cases within 5～10 μg/ml with effective rate of 89.1%;22 cases within 10～15 μg/ml with effective rate of 72.7%;6 cases within 15～20 μg/ml with effective rate of 83.3%;5 cases 20 μg/ml with effective rate of 80.0%.Conclusion Low concentration of theophylline can effectively control the symptom of acute exacerbation of COPD." @default.
- W2364891336 created "2016-06-24" @default.
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- W2364891336 date "2011-01-01" @default.
- W2364891336 modified "2023-09-26" @default.
- W2364891336 title "Monitoring and Analysis of Theophylline Blood Concentration in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease" @default.
- W2364891336 hasPublicationYear "2011" @default.
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