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- W2364913556 abstract "Objective: To detect the expression and relation among P16 protein,vascular endothelial growth factor(VEGF) and microvessel density(MVD) in gastrointestinal stromal tumor as well as clinicopathological significance.Methods: Expression of P16 protein,VEGF and MVD were tested in 68 gastrointestinal stromal tumor tissues with SP immunohistochemical methods.Results: The positive expression rate of P16 protein and VEGF was respectively 52.9%,47.1% and MVD was 23.2±9.43.Expression of P16 and VEGF was significantly correlated with the risk of invasion respectively(both P0.05).MVD was significant correlated with the tumor site and the risk of invasion(both P0.05).There are negative correlation between P16 and VEGF,and between P16 and MVD.Positive correlation was found between VEGF and MVD.Conclusion: P16,VEGF and MVD may be cooperative effects in the development of gastrointestinal stromal tumor,and they could be used as important markers for the biologic behaviors of gastrointestinal stromal tumor." @default.
- W2364913556 created "2016-06-24" @default.
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- W2364913556 date "2007-01-01" @default.
- W2364913556 modified "2023-09-25" @default.
- W2364913556 title "Expression of P16 and VEGF and Microvessel Density in Gastrointestinal Stromal Tumor and Their Clinic Significance" @default.
- W2364913556 hasPublicationYear "2007" @default.
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