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- W2364931054 abstract "Objective To observe the role of glimepiride in improving insulin sensitivity in poorly controlled type 2 diabetes mellitus(T2DM) patients.Methods Totally 56 patients with poorly controlled T2DM were enrolled in this study and randomly divided into control group(26 cases) and the observation group(30 cases).The control group received increased insulin in addition to baseline insulin dosage,and the observation group was treated with glimepiride in addition to the conventional treatment plan.Body mass index(BMI),blood glucose(fasting blood glucose(FBG) and glucose postprandial(2 hPG)),glycated hemoglobin(HbA1c),insulin dosage,treatment and incidence of hypoglycemia were recorded and compared.Results Eight weeks after treatment,the observasion group had significantly lower BMI,FBG and 2 hPG,HbA1c,insulin dosage,and incidence of hypoglycemia than in the control group(P0.05).Conclusion Glimepiride can effectively reduce of FBG,2 hPG and HbA1c levels,reduce the dosage of insulin,hypoglycemia is low,help patients achieve HbA1c compliance,and thus increase the insulin sensitivity in patients with poorly controlled T2DM." @default.
- W2364931054 created "2016-06-24" @default.
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- W2364931054 date "2012-01-01" @default.
- W2364931054 modified "2023-09-23" @default.
- W2364931054 title "Clinical Effectiveness of Glimepiride in Improving Insulin Sensitivity" @default.
- W2364931054 hasPublicationYear "2012" @default.
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